Data center networks are vulnerable and easily plagued by long-term stealthy malicious attacks, which cannot be recognized by measurement based on host cardinality. Thus, this paper presents a novel detector for persistent spreads based on Bloom filter. In our design, multi-stage filter structure is proposed which can achieve high operation speed and low memory consumption because only filtered sips are calculated. Due to the nature of Bloom filter, false negative ratio (FNR) equals 0 all the time. The ideas and mechanisms are illustrated using different traces collected from real networks. Extensive experimental results based on real traces show that the proposed detector has better accuracy than other existing approaches.